You can use as many Regular Expression Filters as you like - they will each apply in the order you put them in.

Match Value: Choose from the following to match on
Match Type: Choose whether this filter will add additional jobs, or remove jobs.

Example - combine two Regular Expression Filters in this way:
One with a Regular Expression of ".*_Nightly" for a Match Value of "Job name", and a Match Type of "Include Matched",
And another with a Regular Expression of ".*site:deploy.*" for a Match Value of "Maven configuration", and a Match Type of "Exclude Unmatched".
This combination creates a view that shows all nightly jobs that also deploy a Maven site.